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CJC-1295 with DAC Anti Aging CJC-1295 Peptide Hormones Acetate Growth Steroid

Categories Polypeptide Hormones
Brand Name: steriodshow
Model Number: 863288-34-0
Certification: SGS,ISO9001,UKAS
Place of Origin: china manufactuer
MOQ: 10g
Price: Negotiation
Payment Terms: Western Union, MoneyGram, T/T,Bitcoin
Supply Ability: plent of stock
Delivery Time: within 12hours after payment
Packaging Details: Special disguised packaging or as your demand
Product name: CJC-1295 with DAC
Synonyms: CJC1295/DAC, CJC-1295 with dac, CJC 1295
Molecular Formula: 165H269N47O46
Molecular Weight: 3647.19
Appearance: White Powder
Purity: 98.71%
Usage: Can be used as pharmaceutical raw material
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    CJC-1295 with DAC Anti Aging CJC-1295 Peptide Hormones Acetate Growth Steroid

    Polypeptide Hormones CJC-1295 with DAC Anti Aging Hormones Acetate Growth Hormone CJC-1295


    1. Quick Detail:

    Unit Size :2 mg/vial
    Unit Quantity :1 Vial
    CAS NO. :863288-34-0
    Synonyms :CJC1295/DAC, CJC-1295 with dac, CJC 1295
    Molecular Formula :C165H269N47O46
    Molecular Weight :3647.19
    Sequence :H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-

    Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2
    Appearance :White Powder
    Purity :98.71%
    Identity (ESI-MS) :3647.19±3.0
    Source :Chemical Synthesis
    Storage :Lyophilized CJC-1295 W/ DAC is stable at room temperature for 90 days,however it should be stored in a freezer

    below -8C for any extended period of time. After reconstituting CJC-1295 W/ DAC should be

    refrigerated at temperatures not to exceed 36 F.

    2. Description:

    CJC-1295 is a derivative of human GH-releasing factor1-29(HGRF1-29). HGRF1-29 is a naturally

    occurring peptide that is actually a truncated form of a larger peptide that binds to the growth hormone

    secretagogue receptor (GHS-R) and causes the release of growth hormone. CJC-1295 has

    four amino acids substituted in its chain that result in strong binding to serum albumin and

    prolong its half-life in the body.

    Because of the way CJC-1295 is engineered its half life has been extended from ~7 minutes to

    greater than 7 days!. This is convenient as it means the product only needs to be injected

    1-2 times per week for continuously elevated levels of Human Growth Hormone (HGH) and

    IGF-1. A single subcutaneous (sc) injection results in measurable quantities of CJC-1295

    in the blood for up to 13 days. Additionally, a single dose of 60 ug/kg of CJC-1295 results in

    elevated levels of growth hormone (125%) while the pulsatile secretion of GH is

    maintained. Furthermore, 60 ug/kg of CJC-1295 elevated IGF-1 levels to the upper limit of normal.

    A dose of 30 ug/kg of CJC-1295 given weekly maintained its response with no evidence of

    desensitization.

    The advantage of using CJC-1295 instead of actual HGH injections is that injecting HGH

    shuts down the body's own natural

    production and therefore when injections are ceased, the body’s ability to produce it's own HGH may

    be impaired and take some time to recover. Since CJC-1295 only stimulates the body's own HGH

    production, this risk is not apparent.

    Another very positive benefit of CJC-1295/CJC-1293 is its ability to promote slow wave sleep.

    Slow wave sleep is also known as deep sleep and is the

    portion of sleep responsible for the highest level of muscle growth and memory retention. SWS are

    decreased significantly in older adults and also with people who tend to exercise later in the evening.

    This peptide has a benefit to side effect ratio that exceeds all others currently being legally sold and

    would make a great addition to ones training regimen or post cycle therapy.

    Clinical Research was first conducted for CJC-1295 during the mid-2000s. The objective of the peptide

    was to treat visceral fat deposits in obese AIDS patients, as increased levels of exogenous hgH are

    presumed to increase lipolysis (fat loss). The clinical research was ultimately successful for most

    research subjects.


    Product Picture:

    3. Applications:

    Those looking for anti-aging benefits, improved physique and sense of well being.

    Administration of single doses of CJC-1295 resulted in a 2- to 10-fold increase in mean

    serum GH levels in all dosing groups, which was dose incremental and persisted for up to 6 days.

    Similarly, a dose-related increase in mean serum IGF-I levels was observed at all dose levels,

    ranging from 1.5- to 3-fold and persisting for up to 14 days. Administration of ascending

    multiple doses of CJC-1295 resulted in elevated levels of GH, similar to those observed after

    a single dose.

    In contrast, elevations in IGF-I levels showed a progressive effect over time, particularly in

    subjects receiving CJC-1295 every 7 d. Results of the multiple-dose study suggest both a

    cumulative pharmacokinetic effect [i.e. persistence of elevated predose levels of IGF-I in all dosing

    groups except group 1 (i.e. two injections of 30 µg/kg)] and a pituitary priming effect (i.e.progressively

    greater Cmax and progressively shorter Tmax after serial dosing). The data indicate that a minimum

    dosing interval of 7 d appears reasonable. The most appropriate dosing interval will be determined

    based on actual efficacy and safety data from longerterm therapeutic studies in patients with various

    clinical conditions.No serious adverse reactions were reported in either study. The most frequently

    reported adverse events in subjects receivingCJC 1295 were injection site reactions, consisting of

    transient pain, swelling, and induration that were sometimes accompanied by local urticaria.

    Injection site reactions tended to be more severe and/or prolonged at higher dose levels. Headache,

    diarrhea, and flushing were also observed, with occasional transient and mild hypotension, but

    occurred primarily at higher doses.Adverse effects complicate the use of GH in the treatment of

    HIV-associated metabolic conditions such as wasting and lipodystrophy. Although increases in the

    daily dose of GH from 1 to 6 mg are associated with dose-responsive benefits, doses of 2–3 mg/d

    or greater are associated with edema, arthralgias, and glucose intolerance. These side effects can

    become dose limiting. In the current studies, none of the subjects experienced these adverse effects.

    Future clinical trials on this disorder will confirm whether the use of GHRH rather than GH will

    circumvent these problems, as has been suggested in recent publications.

    In summary, a single sc administration of CJC-1295 produced sustained elevations of serum GH

    and IGF-I levels in normal subjects for nearly 2 wk. Weekly or biweekly administration of CJC-1295

    resulted in stimulation of GH and IGF-I secretion for at least 7 d. Both single and multiple doses of

    CJC-1295 over 2 wk were safe and generally well tolerated, particularly at doses of 30 and 60 µg/kg.

    Future studies are indicated to evaluate the clinical utility of treatment with CJC-1295 in patients with

    intact GH secretory capacity.

    Now for any GH releaser’s benefits to reach full potential, somatostatin has to be controlled because

    it will inhibit gh release. Using an agent known as an Acetylcholinesterase inhibitor will allow acetyl

    chlorine levels to rise by preventing acethylcholineesterase from overriding acetylcholine; acetylcholine

    will inhibit somastostatin production. An example of a natural acetylcholinieestarase would be

    Huzperine A. A recommended dosage for HuzperineA would be around 50mcg. Now as mentioned

    before a more potent pharm grade somastostatin inhibitor would be Ipamorelin.

    Logically speaking it would make PERFECT sense to combine CJC-1295 with Ipamorelin since

    you get the increase in GH from CJC and the increase of GH pulse frequencies with a reduction in

    somatostatin from the Ipamorelin. This leads to a maximal GH release effect, thus allowing for

    maximum anabolism from optimized GH without desensitization.

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    increasing binding affinity to the GHRH receptors

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    improved physique and sense of well being

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    Competitive Advantages:

    Hello,Zhuhaishi Shuangbojie Technology Co.,ltd is a leading worldwide professional manufacture of
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    1. Rich experience.
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    Genuine and 100% Guarantee on all orders you place. We Have the Best you will come across Online.
    We, As well Provide Tracking on Packages as they are being sent.Our MOQ is 10grams,any trial order
    is welcome,you can make decisions of committing to buying in bulk once our product has been tested.
    4. Experiential shopping
    Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how
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    5. Good after-sales service.
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