Mechano Growth Factor Bodybuilding Injectable Peptide Mgf 2Mg /
Unit Size :2 mg/vial
Synonyms: MGF, Mechano Growth Factor, IGF-1Ec
Molecular Formula : C121H200N42O39
Molecular Weight :2948.15
Appearance :White Powder
Source :Chemical Synthesis
Storage :Lyophilized Peg MGF is stable at room temperature for 90
days,however it should be stored in a freezer below -8C for any
extended period of time. After reconstituting Peg MGF should be
refrigerated at temperatures not to exceed 36 F.
MGF (Mechano Growth Factor) also known as IGF-1Ec is a growth
factor/repair factor that is derived from exercised or damaged
muscle tissue. It’s called MGF as IGF-IEa is a bit of a mouthful
and harder to identify amongst the other IGF variants.It does so
both by activating muscle stem cells and satellite cells, but also
via various other anabolic processes. It differs from “regular”
IGF-1 mainly due to it’s C-Terminal sequence.
MGF has the ability to cause wasted tissue to grow and improve by
activating muscle stem cells and increasing the upregulation of
protein synthesis, this unique ability can rapidly improve recovery
and speed up muscle growth. MGF can initiate muscle satellite
(stem) cell activation in addition to its IGF-1 receptor domain
which, in turn, increases protein synthesis turnover; therefore, if
used correctly it can improve muscle mass over time.
Mechano growth factor (MGF) is a novel splice variant of the IGF-1,
also known as IGF-1 Ec in humans and IGF-1Eb in rodents. It is
actually originally called MGF because the RNA form of it is
expressed in muscle tissues in response to the overload or/and
damage of muscle growth tissue. The C-terminal peptide of the MGF
is a crucial region for the alternative splicing of the peptide.
The alternative splicing in the MGF is brought about by the shift
in the reading frame. In which a specific C-terminal sequence
(E-domain) is encoded by exon 5 and the first part of the exon 6.
Another interesting point in MGF is that, because of the E domain
it contains, MGF can act on muscles independently from the rest of
HOW TO USE :
When you train, what happens to your muscles is they break down,
the cells are damaged, muscle tissue needs to be repaired and your
body produces 2 forms of MGF splice variant. The first initial release of the above mentioned number 1 variant
from the liver helps muscle cell recovery, if there is no MGF then
muscle cells die.
Now, with synthetic injections of MGF you can increase the pulse
and so speed up recovery, and increase the muscle tissue cells by
stimulating satellite cells into full maturity. In terms of dosages, 200mcg bi-laterally is the very best choice of
dosing in muscles trained.
The only problem with MGF, it has such a short half life, just a
few minutes, between 5-7, and it needs to be used immediately post
workout as it wont work if muscle tissue hasn't been damaged. That's why, for me personally, the best option is PEG MGF.
Nevertheless, MGF has a huge role to play, and is administered to
those with muscle wasting diseases and for those who are elderly
and have lost muscle mass for good reason, it is EXTREMELY
White to off white powder
When mechanical overload is introduced to a muscle , the IGF-1 gene
released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec . This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to
grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new
protein synthesis. After this initial splicing of IGF-1 into MGF, production then
switches towards producing a systemic release of IGF-1Ea from the
liver, which also upregulates protein synthesis as well.MGF is available as an injectable peptide, and it has been
anecdotally shown that injecting it will cause a response in the
area resulting in localized muscle growth.
A typical protocol would be:
100-300mcg of MGF divided into 1-2 bilateral administrations in 2-5
different areas of the muscles approximately 5-7 days a week –
Example, if you want to administer 200mcg of MGF into the chest and
biceps muscles 2 times a day and 3 different areas of the muscle
then you would need to divided the dose as follows:
200mcg / 2 times per day = 100mcg per administration
100mcg per administration / 4 muscles (2 chest and 2 bicep muscles)
= 25mcg per muscle
25mcg per muscle / 3 different locations on each muscle = 8.3mcg
Theoretically, the more locations used to administer the MGF into
the muscle the more places for muscle growth.
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